QT interval analysis in individuals with idiopathic mitral valve prolapse

Authors

  • Riyadh Abdullah Jasim Babylon Health Directorate, Ministry of Health, Babylon, Iraq.
  • Alaa Yousif Hassan Babylon Health Directorate, Ministry of Health, Babylon, Iraq.
  • Sabah Abed Shadhar Babylon Health Directorate, Ministry of Health, Babylon, Iraq.

DOI:

https://doi.org/10.22317/imj.v7i1.1221

Keywords:

Analysis, QT interval, Idiopathic mitral valve prolapse

Abstract

Objectives: The goals of the study are to determine whether or not there is a correlation between the QT interval and IMVP, to provide an explanation for sudden cardiac death in some cases, and to show how IMVP symptoms are linked to certain arrhythmias.

Methods: QTC intervals were measured in 43 patients with idiopathic mitral valve prolapse (11 men and 32 women with mean age 46±17 years). All patients underwent a clinical and echocardiographic examination, and ECG taking to assess the incidence of long QT in patients with IMVP.

Results: The data show that 36 of the 43 patients with IMVP have a prolonged QT interval, while only 2 of the 38 patients in the control group have. There was also an uptick in arrhythmia cases when the QT interval was prolonged.

Conclusion: Individuals with IMVP have an increased risk of arrhythmias, and this risk is even greater in patients with very long QT, which can cause life-threatening ventricular arrhythmias, as shown by this study.

References

Hosseini S, Rezaei Y, Samiei N, et al. Effects of mitral valve repair on ventricular arrhythmia in patients with mitral valve prolapse syndrome: A report of two cases. Int J Cardiol. 2016;222:603-605.

Han HC, Ha FJ, Teh AW, et al. Mitral Valve Prolapse and Sudden Cardiac Death: A Systematic Review. J Am Heart Assoc. 2018;7(23):e010584.

van Wijngaarden AL, de Riva M, Hiemstra YL, et al. Parameters associated with ventricular arrhythmias in mitral valve prolapse with significant regurgitation. Heart. 2021;107(5):411-418.

Turker Y, Ozaydin M, Acar G, et al. Predictors of ventricular arrhythmias in patients with mitral valve prolapse. Int J Cardiovasc Imaging. 2010;26(2):139-145

İmamoğlu EY, Eroğlu AG. QT dispersion and ventricular arrhythmias in children with primary mitral valve prolapse. Turk Pediatri Ars. 2016 Sep 1;51(3):135-141.

Kehara H, Minakata K, McCarthy J, Sunagawa G, Mangukia C, Brann S, Zhao H, Boova R, Toyoda Y. Early and late results of mitral valve repair with anterior leaflet patch augmentation. Interact Cardiovasc Thorac Surg. 2022 Jul 9;35(2):ivac144.

Delling FN, Gona P, Larson MG, et al. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014;27(1):17-23.

Tong J, Yew M, Huang W, Yong QW. The Dance of Death: Cardiac Arrest, Mitral and Tricuspid Valve Prolapses, and Biannular Disjunctions. CASE (Phila). 2021;6(3):95-102.

Essayagh B, Sabbag A, Antoine C, et al. Presentation and Outcome of Arrhythmic Mitral Valve Prolapse. J Am Coll Cardiol. 2020;76(6):637-649.

Okada Y, Inoue N, Fukushima N, Yoshikawa T, Takahashi Y, Matsubara S, Hasegawa Y. Idiopathic mitral valve chordae rupture in an infant: importance of rapid diagnosis and surgery. Pediatr Int. 2015 Apr;57(2):e65-8.

Gasser S, Reichenspurner H, Girdauskas E. Genomic analysis in patients with myxomatous mitral valve prolapse: current state of knowledge. BMC Cardiovasc Disord. 2018;18(1):41.

Nagata Y, Bertrand PB, Levine RA. Malignant Mitral Valve Prolapse: Risk and Prevention of Sudden Cardiac Death. Curr Treat Options Cardiovasc Med. 2022;24(5):61-86.

Nordhues BD, Siontis KC, Scott CG, et al. Bileaflet Mitral Valve Prolapse and Risk of Ventricular Dysrhythmias and Death. J Cardiovasc Electrophysiol. 2016;27(4):463-468.

Gloria Vassilikì Coutsoumbas, Giuseppe Di Pasquale, Mitral valve prolapse with ventricular arrhythmias: does it carries a worse prognosis?, European Heart Journal Supplements, Volume 23, Issue Supplement_E, October 2021, Pages E77–E82, https://doi.org/10.1093/eurheartj/suab096

Mohammadieh AM, Dissanayake HU, Sutherland K, Ucak S, De Chazal P, Cistulli PA. Does obstructive sleep apnoea modulate cardiac autonomic function in paroxysmal atrial fibrillation? [published online ahead of print, 2022 Apr 9]. J Interv Card Electrophysiol. 2022;10.1007/s10840-022-01202-3.

De Bonis M, Lapenna E, Taramasso M, et al. Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: up to 21 years of clinical and echocardiographic results. J Thorac Cardiovasc Surg. 2014;148(5):2027-2032.

Hodzic E. Assesment of Rhythm Disorders in Classical and Nonclassical Mitral Valve Prolapse. Med Arch. 2018;72(1):9-12.

İmamoğlu EY, Eroğlu AG. QT dispersion and ventricular arrhythmias in children with primary mitral valve prolapse. Turk Pediatri Ars. 2016;51(3):135-141.

Topilsky Y, Michelena H, Bichara V, Maalouf J, Mahoney DW, Enriquez-Sarano M. Mitral valve prolapse with mid-late systolic mitral regurgitation: pitfalls of evaluation and clinical outcome compared with holosystolic regurgitation. Circulation. 2012;125(13):1643-1651.

Clementy N, Bisson A, Challal F, et al. Nonsustained Ventricular Tachycardia at the Time of Implantation Predicts Appropriate Therapies on Rapid Ventricular Arrhythmia in Primary Prevention Patients With Nonischemic Cardiomyopathy: Results From the Very-High-Rate Registry. JACC Clin Electrophysiol. 2017;3(11):1338-1339.

Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135(25):e1159-e1195.

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Published

2023-03-26

How to Cite

1.
Jasim RA, Hassan AY, Shadhar SA. QT interval analysis in individuals with idiopathic mitral valve prolapse. Iraq Med J [Internet]. 2023 Mar. 26 [cited 2024 Nov. 25];7(1):13-6. Available from: https://mail.iraqmedj.org/index.php/imj/article/view/1221

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